Iqbal Sayeed Selected Research

Inflammation (Inflammations)

5/2020	Progesterone Attenuates Stress-Induced NLRP3 Inflammasome Activation and Enhances Autophagy following Ischemic Brain Injury.
11/2016	Progesterone treatment shows greater protection in brain vs. retina in a rat model of middle cerebral artery occlusion: Progesterone receptor levels may play an important role.
1/2016	Neuroprotection by progesterone after transient cerebral ischemia in stroke-prone spontaneously hypertensive rats.
9/2015	Progesterone and vitamin D combination therapy modulates inflammatory response after traumatic brain injury.
2/2014	Delayed progesterone treatment reduces brain infarction and improves functional outcomes after ischemic stroke: a time-window study in middle-aged rats.
5/2011	Genomic profile of Toll-like receptor pathways in traumatically brain-injured mice: effect of exogenous progesterone.
11/2010	Progesterone and allopregnanolone attenuate blood-brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases.
10/2009	Development and screening of water-soluble analogues of progesterone and allopregnanolone in models of brain injury.
1/2009	Progesterone as a neuroprotective factor in traumatic and ischemic brain injury.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Iqbal Sayeed Research Topics

Disease

24	Traumatic Brain Injuries (Traumatic Brain Injury) 08/2023 - 04/2006
18	Stroke (Strokes) 01/2019 - 05/2004
16	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2019 - 04/2006
15	Brain Injuries (Brain Injury) 05/2020 - 01/2007
14	Ischemic Stroke 01/2019 - 04/2006
14	Infarction (Infarctions) 01/2019 - 05/2004
10	Ischemia 05/2020 - 05/2004
9	Inflammation (Inflammations) 05/2020 - 01/2009
8	Brain Ischemia (Cerebral Ischemia) 05/2020 - 05/2004
8	Body Weight (Weight, Body) 01/2016 - 01/2002
4	Hypoxia (Hypoxemia) 09/2015 - 01/2014
3	Edema (Dropsy) 01/2017 - 04/2006
3	Cerebral Infarction 03/2015 - 01/2007
3	Contusions 08/2013 - 04/2006
3	Wounds and Injuries (Trauma) 01/2011 - 04/2006
3	Parkinson Disease (Parkinson's Disease) 03/2006 - 02/2003
2	Neuroinflammatory Diseases 01/2020 - 09/2015
2	Perceptual Disorders (Hemispatial Neglect) 05/2016 - 02/2014
2	Reperfusion Injury 03/2015 - 02/2013
2	Brain Infarction 09/2014 - 02/2014
2	Brain Edema (Cerebral Edema) 10/2009 - 04/2006
2	Necrosis 10/2009 - 01/2009
2	Parkinsonian Disorders (Parkinsonism) 10/2003 - 02/2003
1	COVID-19 related pediatric multisystem inflammatory disease 01/2022
1	COVID-19 01/2022
1	Craniocerebral Trauma (Head Injury) 12/2020
1	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 02/2018
1	Intracranial Vasospasm 02/2018
1	Transient Ischemic Attack 01/2016
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 09/2015
1	Carotid Stenosis (Carotid Artery Stenosis) 07/2015
1	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 07/2015
1	Thrombosis (Thrombus) 07/2015
1	Cognitive Dysfunction 07/2015
1	Spinal Cord Injuries (Spinal Cord Injury) 05/2015
1	Ischemic Optic Neuropathy (Anterior Ischemic Optic Neuropathy) 05/2015
1	Vascular Diseases (Vascular Disease) 01/2015

Drug/Important Bio-Agent (IBA)

43	Progesterone FDA LinkGeneric 01/2023 - 04/2006
13	Neuroprotective AgentsIBA 11/2017 - 03/2006
9	Hormones (Hormone)IBA 01/2019 - 07/2009
7	Biomarkers (Surrogate Marker)IBA 08/2023 - 02/2014
7	Vitamin D FDA LinkGeneric 01/2019 - 07/2009
5	salicylhydroxamic acid (SHAM)IBA 11/2017 - 01/2011
4	NeurosteroidsIBA 01/2019 - 04/2006
4	CytokinesIBA 11/2017 - 01/2009
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 09/2011
4	Pregnanolone (Allopregnanolone)IBA 11/2010 - 04/2006
4	AntioxidantsIBA 01/2009 - 02/2003
4	Sodium SeleniteIBA 01/2005 - 01/2002
3	OsteopontinIBA 01/2022 - 01/2020
3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2019 - 01/2014
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2014
3	Matrix Metalloproteinases (MMPs)IBA 01/2014 - 11/2010
2	OximesIBA 01/2023 - 05/2012
2	LipidsIBA 01/2017 - 01/2002
2	Glial Fibrillary Acidic ProteinIBA 05/2016 - 02/2014
2	NF-kappa B (NF-kB)IBA 01/2015 - 12/2009
2	cresyl violetIBA 02/2014 - 11/2010
2	Tissue Plasminogen Activator (Alteplase)FDA Link 02/2014 - 01/2014
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 04/2013 - 07/2010
2	Caspase 3 (Caspase-3)IBA 09/2011 - 05/2004
2	GangliosidesIBA 01/2004 - 01/2002
2	CholesterolIBA 01/2004 - 01/2002
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2004 - 01/2002
2	thiobarbituric acidIBA 01/2004 - 01/2002
2	Thiobarbituric Acid Reactive SubstancesIBA 01/2004 - 01/2002
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2004 - 01/2002
2	Oxidopamine (6 Hydroxydopamine)IBA 10/2003 - 02/2003
2	Oxidants (Oxidizing Agents)IBA 10/2003 - 02/2003
1	ProdrugsIBA 01/2023
1	C-Reactive ProteinIBA 01/2022
1	Interleukin-6 (Interleukin 6)IBA 01/2022
1	Ferritins (Ferritin)IBA 01/2022
1	SteroidsIBA 05/2020
1	InflammasomesIBA 05/2020
1	NLR ProteinsIBA 05/2020
1	HMGB1 Protein (HMG1)IBA 05/2020
1	Immunoglobulin G (IgG)IBA 01/2019
1	Chloroquine (Aralen)FDA LinkGeneric 01/2019
1	Immunoglobulins (Immunoglobulin)IBA 01/2019
1	Nerve Growth Factors (Neurotrophins)IBA 11/2017
1	EmulsionsIBA 01/2017
1	phospholipid emulsion soybean oil (Intralipid)IBA 01/2017
1	Progesterone Receptors (Progesterone Receptor)IBA 11/2016
1	Superoxides (Superoxide)IBA 01/2016
1	Toll-Like Receptors (Toll-Like Receptor)IBA 09/2015
1	EdaravoneIBA 07/2015
1	Free Radical ScavengersIBA 07/2015
1	ethyl 6- (N- (2- chloro- 4- fluorophenyl)sulfamoyl)cyclohex- 1- ene- 1- carboxylateIBA 03/2015
1	Protein Kinases (Protein Kinase)IBA 03/2015
1	Toll-Like Receptor 4IBA 03/2015
1	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2015
1	Calcitriol (Calcijex)FDA LinkGeneric 01/2015
1	Tight Junction ProteinsIBA 01/2015

Therapy/Procedure

4	Therapeutics 01/2019 - 01/2012
4	Injections 01/2016 - 04/2006
2	Subcutaneous Injections 11/2017 - 01/2014
2	Intraperitoneal Injections 11/2017 - 01/2012
2	Sutures (Suture) 01/2012 - 04/2006
1	Ligation 06/2015